Department of Surgery
School of Medicine Queen's University
 

Dr Mike Hendry

Dr Mike Hendry Plastic SurgeonUniversity Position:
Assistant Professor

Current Appointment:
Attending Staff, Kingston Health Sciences Centre

Areas of Clinical Interest:
Complex hand, wrist and peripheral surgery

Areas of Research Interest:
The basic science and enhancement of peripheral nerve regeneration






Contact Information:
Hotel Dieu Hospital
166 Brock Street
Kingston, Ontario
K7L 5G2
Tel: (613) 544-3400 x. 2117
Fax: (613) 545-0576


Education and Professional Qualifications

2017-18

    
Clinical Fellowship – Orthopedic Hand and Upper Extremity Surgery,
Harvard Medical School; Beth Israel Deaconess Medical Center, Boston, MA. 

2017

Full Licensure for Independent Practice, Massachusetts Board of Registration, #269345
2017

Independent Licensure, College of Physicians and Surgeons of Ontario, #93070

2017

Fellow of the Royal College of Physicians and Surgeons of Canada

2014

Clinical Investigator Program, Royal College of Physicians and Surgeons of Canada

2014

Masters of Science, Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada
2012-13                       Canadian Institute of Health Research (CIHR): Training Program in Regenerative Medicine.  University Health Network and in association with the University of Toronto, Toronto, Ontario
2011

Licentiate of the Medical Council of Canada, Medical Council of Canada.

2010-17



Postgraduate Education Certificate of Registration (Medical License for Resident Physicians),College of Physicians and Surgeons of Ontario, Ontario, Canada, #93070.

2010

Doctor of Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
2006

Bachelor of Science (Honours), Department of Biology, Queen’s University, Kingston, Ontario, Canada 



































Professional Memberships

2018 American Medical Association
2017 Royal College of Physicians and Surgeons of Canada
2014 Candidate member, American Society for Peripheral Nerve
2014 Member, Plastic Surgery Research Council
2013 Student Member, Society for Neuroscience
2011 Resident Member, American College of Surgeons
2011 Resident Member, American Society of Plastic Surgeons
2010 Junior Member, Canadian Society of Plastic Surgeons
2008 Member, Ontario Medical Association
2008 Member, Canadian Medical Association


Publications

Peer Reviewed Manuscripts Published or in Press

Hendry, JM, Alvarez-Veronesi MC, Placheta, E, Zhang JJ, Gordon T, Borschel GH. 2016. ErbB2 blockade with Herceptin (trastuzumab) enhances peripheral nerve regeneration after repair of acute or chronic peripheral nerve injury. Annals of Neurology 80(1): 112-126.

Placheta, E., Wood MD, Lafontaine C, Liu E, Hendry JM, Angelov D, Frey M, Gordon T, Borschel GH. 2015. Enhancement of facial nerve motoneuron regeneration through cross-face nerve grafts by adding end-to-side sensory axons. Plastic and Reconstructive Surgery 135: 460-471.

Gordon T, Hendry JM, Lafontaine CA, Cartar H, Zhang JJ, Borschel GH.  2015. Nerve Cross-Bridging to Enhance Nerve Regeneration in a Rat Model of Delayed Nerve Repair. PLoS ONE 10(5): e0127397. doi:10.1371/journal.pone.0127397

Hendry, JM, Alvarez-Veronesi MC, Snyder A, Gordon T, Borschel GH. 2014. Side-to-side nerve bridges support donor axon regeneration into chronically denervated nerves and are associated with characteristic changes in Schwann cell phenotype. Neurosurgery 77(5): 803-813.

Placheta, E, Hendry JM*, Wood MD, Lafontaine CW, Liu EH, Alvarez-Veronesi MC, Frey M, Gordon T, Borschel GH. 2014. The ErbB2 inhibitor Herceptin (Trastuzumab) promotes axon regeneration four weeks after acute nerve transection and repair. Neuroscience Letters 582: 81-86.

Taylor, DW, Petrera M, Hendry M, Theodoropoulos JS.  2011. A systematic review of the use of platelet-rich plasma in sports medicine as a new treatment for tendon and ligament injuries.  Clinical Journal of Sports Medicine 21 (4): 344 – 352.

Hendry, JM, Mainprize J, McMillan C, Binhammer P.  2011.  Structural comparison of the finger proximal interphalangeal joint surfaces and those of the third toe: suitability for joint reconstruction. Journal of Hand Surgery Am 36 (6): 1022-1027.



Published Conference Proceedings

Hendry, JM, Placheta E, Gordon T, Borschel GH. 2013. Abstract 70: Neuregulin-1 / ErbB2 signaling regulates early axonal regeneration following peripheral nerve injury. Plastic and Reconstructive Surgery 131(5S): 58.

Hendry, M, Placheta E, Gordon T, Borschel GH. 2014. Abstract 67: The monoclonal antibody Herceptin improves regeneration after injured nerves are repaired immediately or after a period of chronic denervation. Plastic and Reconstructive Surgery 133(3S): 77.

Hendry, M, E Placheta E, Alvarez-Veronesi C, Gordon T, Borschel GH. 2015. Abstract 118: Monoclonal antibody (Herceptin) mediated enhancement of peripheral nerve motor and sensory axon regeneration operates through a potential new pathway involving ErbB2 and the epidermal growth factor receptor (ErbB1).  Plastic and reconstructive Surgery 135 (5S): 85.



Non-Peer Reviewed: Textbooks and Published Conference Proceedings

Farhangkhoee, H, Hendry M, Leung J. “Plastic Surgery” in Toronto Notes 2010: Comprehensive Medical Reference & Review for MCCQE I & USMLE II. Ed. S. Baxter and G. McSheffrey. Toronto, Type and Graphics Inc., 2010.

Davidge, K,  JM Hendry, R Zuker, GH Borschel,. Chapter 12: Pediatric Facial Nerve Palsies in Facial Nerve Disorders and Diseases, Diagnosis and Management. Eds. O. Guntinas-Lichius and BM Schaitken. Thieme Publishers, Stuttgart, Germany. 2015.

Hendry JM, Dolan, MM. Fixation of Uni and Bicondylar Phalangeal Fractures. in Hand Surgery: Tricks of the Trade.Eds Dr. Pedro K. Beredjiklian and Dr. Michael Vosbikian. Thieme Publisher. In Print.

Knaus W, Hendry JM, Upton J. Proximal Interphalangeal Joint Fracture-Dislocation in Hand Surgery: Tricks of the Trade.Eds Dr. Pedro K. Beredjiklian and Dr. Michael Vosbikian. Thieme Publisher. In Print.



Oral Podium Presentations
International

2016


Canadian Society of Plastic Surgeons Annual Meeting: Ottawa, Ontario. “Multiple nerve cross-bridges support donor axon regeneration into chronically denervated nerves, Schwann cell re-differentiation and enhanced motor endplate re-innervation.”
2016


American Society for Peripheral Nerve – Annual Meeting: Scottsdale Arizona: “Evaluation Of Unmyelinated Axon Regeneration Following Peripheral Nerve Injury: An Alternative To Electron Microscopy”.
2015


Plastic Surgery Research Council – Seattle, WA.  Monoclonal antibody (Herceptin) mediated enhancement of peripheral nerve motor and sensory axon regeneration operates through a potential new pathway involving ErbB2 and the epidermal growth factor receptor (ErbB1)”.
2015


American Society for Peripheral Nerve – Annual Meeting, Paradise Island, Bahamas. “The monoclonal antibody Herceptin enhances peripheral nerve regeneration through a potential new pathway involving ErbB2 and the epidermal growth factor receptor (ErbB1)”. 
2014



Canadian Society of Plastic Surgeons Annual Meeting – Residents Corner Oral Presentation competition, Montreal, QC “The Monoclonal Antibody Herceptin Improves Regeneration After Injured Nerves are Repaired Immediately or After a Period of Chronic Denervation”.
2014


Plastic Surgery Research Council Annual Meeting – New York, New York “The Monoclonal Antibody Herceptin Improves Nerve Regeneration in a Rat Nerve Transection and Repair Model”.
2014


American Society for Peripheral Nerve – Annual Meeting; Kauai, Hawaii. “The Monoclonal Antibody Herceptin Improves Nerve Regeneration in a Rat Nerve Transection and Repair Model”.
2013


Canadian Society of Plastic Surgeons Annual Meeting – General Scientific Session; Calgary, AB. “Neuregulin-1/ ErbB2 signaling regulates early axonal regeneration following peripheral nerve injury”.
2013


Plastic Surgery Research Council Annual Meeting – Los Angeles, CA. “Neuregulin-1/ ErbB2 signaling regulates early axonal regeneration following peripheral nerve injury”.
2009



Canadian Society of Plastic Surgeons Annual Meeting - General Scientific Session - Kelowna B.C. “Structural comparison of the finger proximal interphalangeal (PIP) joint surfaces and those of the 3rd toe regarding suitability for transplantation in PIP joint reconstruction”.











































Local/Institutional

2014



40th Annual Gallie Day – Gallie Bateman & McMurrich Research Presentations, Department of Surgery, University of Toronto, Toronto, ON “The ERBB2 receptor pathway regulates regeneration following the acute and chronic repair of nerve injuries”.
2016


UHN Wound  Care Conference. Wound Care Beyond the Basics: Getting to Zero Pressure Ulcers. Invited Podium Presentation. Toronto – ON. “Surgical Management of Chronic Wounds: Fact and Fiction”.
2016


Resident Research Day - Division of Plastic and Reconstructive Surgery  - Toronto, ON. “Development and Validation A New Protocol to Evaluate Unmyelinated Axon Regeneration without the Need for Electron Microscopy”.
2015




Resident Research Day – Division of Plastic and Reconstructive Surgery  - Toronto, ON.Side-to-side nerve bridges provide evidence of axon-mediated Schwann cell protection within chronically denervated nerves and influence denervated Schwann cell phenotype”.

2014


Resident Research Day – Division of Plastic and Reconstructive surgery – Toronto, ON. “The Monoclonal Antibody Herceptin Improves Nerve Regeneration in a Rat Nerve Transection and Repair Model”.
2013


Annual Regenerative Medicine Symposium – Toronto, ON. “Using side-to-side nerve grafts to improve regenerative outcomes following peripheral nerve injury: investigating the regulatory function of Neuregulin-1.”
2013


Resident Research Day – Division of Plastic and Reconstructive surgery – Toronto, ON. “Protecting against chronic denervation with side-to-side nerve grafts: Investigating the regulatory function of Neuregulin-1.”
2008


Clinical and Organizational Research Ethics. Podium Presentation for the Case Conference at the Joint Center for Bioethics  “The Burden of Substitute Decision-Making”.



































Poster Presentations

2015



American Society for Peripheral Nerve – Paradise Island, Bahamas: “Side-to-side nerve bridges support donor axon regeneration into chronically denervated nerves and are associated with characteristic changes in Schwann cell phenotype and remyelination”.
2014

Society for Neuroscience – Washington, D.C.: “The ErbB2 receptor pathway regulates regeneration following the repair of acute peripheral nerve injuries in a rat model.”
2014


Institute of Medical Science Scientific Day 2014. Alan Wu Poster competition: “ErbB2 inhibition with the therapeutic monoclonal antibody Herceptin® enhances peripheral nerve regeneration in a rat model.”
2013


Society for Neuroscience – San Diego, CA. Poster presentation: “Using side-to-side nerve grafts to improve regenerative outcomes following peripheral nerve injury: investigating the regulatory function of Neuregulin-1.”
2013


Canadian Association of Neuroscience – Toronto, ON. Poster presentation: “Neuregulin-1/ ErbB2 signaling regulates early axonal regeneration following peripheral nerve injury”.
2009


Ontario Medical Student Research Day – Toronto, ON. Poster Presentation: “Structural Comparison of Proximal Interphalangeal (PIP) Joint Surfaces of the fingers and 3rd toe for the purposes of PIP joint reconstruction”.

























Abstracts

2016


American Society for Peripheral Nerve – Scottsdale, Arizona “Gordon T, Hendry JM, Synder-Warwick A, Zhang J, Borschel GH. Side-to-side bridging to promote nerve regeneration after delayed surgical repair”.
2015



Resident Research Day – Division of Plastic and Reconstructive Surgery “Catapano J, MP Willand, U Elbaz, JM Hendry, T Gordon, A Ali, GH Borschel. An animal model of corneal neurotization: studying a novel solution for corneal anesthesia and neurotrophic keratitis”.
2015



American Society for Peripheral Nerve – Paradise Island, Bahamas “ Gordon T, A Ladak, H. Cartar, J Zhang, JM Hendry, GH Borschel. Epineurial Windows are Necessary for Donor Axons to Regenerate Across an Autograft into Recipient Denervated Rat Nerve Stumps: the Axons Grow Equally in Proximal and Distal Directions”
2014





Society for Neuroscience – Washington, D.C.: Gordon T., J.J. Zhang, A. Ladak, A. Snyder-Warwick, JM Hendry, G.H. Borschel. Improved peripheral motor and sensory nerve regeneration after delayed repair of transected common peroneal (CP) nerve is promoted by prior side-to-side bridging from a donor intact tibial nerve (TIBdonor) to the 3m chronically denervated common peroneal nerve stump (CPden) in an experimental Sprague Dawley rat model”






















Patents

2014

Full US and worldwide patent application reference # 499-020-P. “ErbB2 receptor and nerve regeneration” Serial No. US 61/987,692.





Industry Collaboration

2015

PlantForm Corporation. Specializing in plant derived manufacturing of antibody pharmaceuticals, including trastuzumab (Herceptin).





Updated Aug 16, 2018