Department of Surgery
School of Medicine Queen's University

Dr Jay Engel

Dr Jay Engel Surgical OncologyUniversity Position:
Associate Professor, Department of Surgery
Chair of Surgical Oncology  

Current Appointment:
Attending Staff, Kingston Health Sciences Centre
Joint-Appointment with Department of Surgical Oncology

Areas of Clinical Interest:
Breast, Melanoma, Sarcoma

Areas of Research Interest:
Breast cancer

Contact Information:
Cancer Clinic - Burr 2
Room 060
Kingston General Hospital
76 Stuart Street
Kingston, ON
K7L 2V7
Tel: (613) 549-6666 x 6651
Fax: (613) 548-2500

Click here to email Dr Engel

• Nov 1990 – Jul 1992
Visiting Assistant Professor, Surgical Oncology Fellowship
Los Angeles, California

• Jan 1990 – Nov 1990       
Surgical Oncology Fellowship

• Jul 1985 – Jun 1989       
General Surgery Residency

• Jun 1984 – Jun 1985       
Rotating Internship
Scarborough General Hospital, Scarborough, Ontario

Medical School Graduation:
• Oct 1978 – Jun 1984       
Dublin, Ireland

Professional Memberships:
• Canadian Society of Surgical Oncologists
• Executive member at large
• Canadian Association of Clinical Surgeons
• Canadian Association of General Surgeons
• Radiation Oncology Tumor Group
• Royal College of Physicians and Surgeons of Canada
• Canadian Medical Association
• Ontario Medical Association
• London Academy of Medicine

• Cancer Care Ontario Stage Capture Project: - Stage Lead and Clinician Mentor, London Health Sciences Centre 2007- 2008
• National Advisory Panel on Management of the Axilla – 2006
• London Region Cancer Program, Small Grants Competition – Scientific Officer 2005 - 2007           
• Cancer Care Ontario, Quality Indicators for Colorectal Cancer Committee 2005- 2006
• Ontario Cancer Research Network (OCNR)
• Tumor Banking Committee  Oct 2004 - 2007 
• Cancer Care Ontario Practice Guidelines Committee – Sarcoma Group
• RCPSC – Specialty Committee Surgical Oncology 2002-2006
• Breast Assessment Committee Apr 2004  
• Pre-Admit Clinic Committee – LHSC – 2003-2004
• President South Western Ontario Surgical Association (2003-2004)
• Chair Gastrointestinal Disease Site Team 2001-2003
• President University of Western Ontario Surgical Alumni Association (2001-2003)     
• Ontario Cancer Genetics Network – Chair for London Group 1995-2002
• Ontario Cancer Genetics Network Management Committee-1995-2002
• Ontario Cancer Genetics Network Clinical Resource Group – Executive Committee 1995-2002
• UWO Phase IV OSCE Exam committee – Developed Surgical component 1994, 1995, 1996
• Translational Breast Research Centre – Steering Committee
• Breast Assessment Program, Cancer Care Ontario, Southwest Region – Steering Committee
• Cancer Quality Council Ontario

Awards and Distinctions:
• UWO Surgical Oncology Teaching Award 2005
• R. Samuel McLaughlin Foundation Fellowship Award (1991)
• Ontario Ministry of Health
• Health Research Personnel Development Program Fellowship Award (1990)
• Philips Prize for Resident Research in Radiation Oncology (1990)
• General Surgery Resident Research Prize (1987)
• Ontario Scholar (1975)
• Social Sciences Award (1975)

Gastrointestinal Stromal Tumours - Multidisciplinary Case Based Discussion. London, ON. Jan 2008

Colorectal Cancer Update 2007, Prevention and Treatment, London, ON. Jan 31 2007

Surgical Management of Breast Cancer. Surgical Oncology Family Practice Retreat. London, ON. April, 2006.

Breast Cancer Update: A Surgical Perspective, Chatham, ON, December 15, 2005       
Retroperitoneal Sarcomas, South Western Ontario Surgical Association, London, ON
November 11, 2005               

Melanoma: The Black Spot, General Surgery Conference, London, ON   September 16, 2005

Gastric MALT Lymphomas, South Western Ontario Gastroenterology Association Annual Meeting, Collingwood, On June 2004

Management of Patients at Risk for Inherited Breast & Colon Cancer. Windsor, On.  Nov 19th, 2003

Sentinel Lymph Node: Surgical Perspective, The Eastern Great Lakes Chapter, Society of Nuclear Medicine 23rd Annual Meeting, Oakville, On.   Oct 2nd, 2003

Colon Cancer Surveillance – South Western Ontario Gastroenterology Association Annual Meeting, Taboo Resort Muskoka, On. - June 14th, 2003

Follow up of Colorectal Cancer Patients – South Western Ontario Surgical Association Annual Meeting – November 6th, 2001

Advances in Management of Gastric Adenocarcinoma, Rocky Crest Resort, August 26th, 2002
Villous Adenomas of the Rectum, South Western Ontario Gastroenterology Association Annual Meeting, Muskoka Sands Resort, On. June 9th, 2001

Sentinel Node Biopsy in Breast Cancer,   “Is it the Standard of Care?”  St. Joseph’s Health Centre, London November 7th, 2001
Sentinel Node Biopsy in Breast Cancer, Elmhurst Inn, Ingersoll, January 24th, 2001

“Sentinel Node Biopsy in Breast Cancer”  New Concepts for a New Century, March 25, 2000

Interdisciplinary Conference on Breast Assessment; Cancer Care Ontario South Western Region “Controversies in the Management of Breast Disease” November 11, 2000

Telemedicine Conference (Toronto Hospital)  “Rectal Cancer: Concepts of Modern Medicine Management”   May 12, 1998
Gayle Sheridan, P J Ainsworth, J H Jung and J. Engel:  “A Multidisciplinary Approach to Identifying High Risk Families In South western Ontario”  Genetics Society of Canada, July 1997 (Poster Presentation)

Tumour Angiogenesis Predicts Recurrence in Invasive Colorectal Cancer”  Royal College of Surgeons in Ireland Second North American Alumni Meeting, Toronto Colony Hotel,
Toronto, Ontario  April 22, 1995

“Necrotizing Fasciitis and Myositis” 10th Annual Critical Care Conference,  Best Western Lamplighter Hotel  May 26, 1995

“Future Trends in the Management of Colorectal Cancer: The Canadian Association for Enterostomal Therapy Radisson Hotel, London  October 5, 1994

“Exploring New Frontiers in the Treatment of Breast Cancer” Recovery Room Conference, Lamplighter Inn, April 16, 1994

“Brachytherapy:  An Option for Adjuvant Radiation Therapy Following Breast Sparing Surgery” Windsor Academy of Surgery, Windsor, Ontario  November 8, 1993

“Brachytherapy: An Option for Adjuvant Radiation Therapy Following Breast Sparing Surgery”  South western Ontario Surgical Association, London, Ontario  November 3, 1993
“Soft Tissue Sarcomas of the Extremities”  Duff Day, University of Western Ontario  June 1993
“Mastectomy, Breast Cancer”  OR Nurses,  March 10, 1993

“Brachytherapy”  OR Nurses/Recovery Room Nurses,  September 17, 1992

“Biological Equivalence of Ytterbium 169 in Cellular and Murine      
Model”  Annual Meeting, Royal College of Physicians and Surgeons of Canada   September 1990
 “Function of the Transplanted Gallbladder in Liver Recipients”      
Annual Meeting, Royal College of Physicians and Surgeons of Canada   September 1988
“Functions of the Transplanted Gallbladder in Liver Recipients:  XII International Congress of the Transplantation Society   August 1988 (Poster Presentation)
“Surgery for Chronic Constipation”  Canadian Association of General Surgeons,  Annual Meeting,  Royal College of Physicians and Surgeons of Canada  September 1987

October 6, 2004         
GIST Tumors – Surgical residents
University of Western Ontario Residents

October 22, 2003         
Sarcoma Lecture – Surgical residents
University of Western Ontario Residents

June 15, 1999          
“Surgical Controversies in Breast Cancer Sharing Perspectives’
Westover Inn, St. Mary’s, Ontario

March 26, 1998       
“Biology of Human Cancer”
University of Western Ontario

October 9, 1996   
“Surgical Management Breast Cancer and Reconstruction”  Pathology Residents

June 22, 1996   
“Screening for Colorectal Cancers in Women”  Postgraduate Course,  The Society of Obstetricians and Gynaecologists of Canada Annual Meeting, Quebec City

March 26 – 28, 1996      
“Surgery and Cancer” 
Department of Pathology and Oncology UWO

December 6, 1995       
“Surgical Issues in Breast Cancer”
London Regional Cancer Centre

November 22, 1995  
“Practical Management of Benign and Malignant Breast Lumps”  A Practical Day in Pathology, UWO, University Hospital, London, Ontario

March 22, 1994      
“Surgery and Cancer”
Biology of Human Cancer Course,  UWO

April 28, 1993          
 “Breast Cancer”
LMCC Preparation Course

Temple CL, Snell LJ, Power SM, Parfitt JR, Scilley C, Engel CJ, Shum D, Chakrabarti S, Joseph MG, Lohmann RC, Ainsworth P. Clinical Significance of the RT-PCR positive sentinel node in melanoma. J Surg Oncol. 2007 Jun 1;95(7):546-54.

Allan Al, George R, Vantyghem SA, Lee MW, Hodgson NC, Engel CJ, Holliday RL, Girvan DP, Scott LA, Postenka CO, Al-Katib W, Stitt LW, Uede T, Chambers AF, Tuck AB. Role of integrin-binding protein osteopontin in lymphatic metastasis of breast cancer. Am J Pathol. 2006 Jul; 169(1):233-46.

Perera F, Chisela, Stitt L, Engel J, Venkatesan V. TLD skin dose measurements and acute and late effects after lumpectomy and high-dose-rate brachytherapy only for early breast cancer. Int J Radiat Oncol Biol Phys. 2005 Aug 1;62(5):1283-90.
Perera F, Yu E, Engel J, Holliday R, Scott L, Chisela F, Vankatesan V. Patterns of breast recurrence in a pilot study of brachytherapy    confined to the lumpectomy site for early breast cancer with six years’ minimum follow-up. Int J Radiat Oncol Biol Phys. 2003 Dec 1;57(5):1239-46.

Engel J,  Genetic Screening of Hereditary Cancer: Breast Cancer  Surgical Oncology News January 2001; 4 - 5

Engel J,  Mammogram versus Palpation The Canadian Journal of Diagnosis  2000; 17 (11):  107 - 111

Temple, C L; Scilley, C G; Engel C J; Shum D T; Lohmann, R ; Mattar, A G; Zabel, P L
Sentinel node biopsy in melanoma using technetium-99m rhenium colloid: The London Experience Ann Plast Surg. 2000; 45(5): 491-9

Fan, Yao-Shan; Rizkalla, Brian F William; and Engel J, Jumping Tranaslocations of 11q in Acute Myeloid Leukemia  and 1q in Follicular Lymphoma Cancer Genet Cytogenet 2000; 118: 35-41

Videtic, Gregory, M.M.: Fisher, Barbara J.; Perera, Francisco E; Bauman, Glenn S; Kocha, Walter I; Taylor, Marianne;  Vincent, Mark D; Plewes, E A; Engel, C Jay; Stitt, Larry W.   
Preoperative Radiation With Concurrent 5-Fluorourancil Continuous Infusion For Locally Advanced Unresectable Rectal Cancer  Int. J. Radiation Oncology Biol. Phys., 1998; 42 (2): 319 - 324
Perera, F; Engel, C J; Holliday, R; Scott, L; Girotti, M; Girvan, D; Chisela, F; and Venkatesan, V Local Resection and Brachytherapy Confined to the Lumpectomy Site for Early Breast Cancer: A Pilot Study Journal of Surgical Oncology 1997; 65:263 – 268
Engel, C J; Chambers, Ann F; Kerkvliet, Nancy; and O’ Malley, Frances, P  Tumor Angiogenesis Predicts Recurrence in Invasive Colorectal Cancer When Controlled for Dukes Staging Am. J. Surg. Pathol 1996:  (10): 1260-1265

O’Malley, Frances P; Engel, C J Breast Cancer: Management of High-Risk Patients
Canadian Journal of CME, February, 1996,  p 81-91

Perera, F; Chisela, F; Engel, C J; Venkatesan, V Method of Localization and Implantation of Lumpectomy Site for High Dose Rate Brachytherapy after Conservative Surgery for T1 and T2 Breast Cancer Int. J. Radiation Oncology Biol. Phys., 1995;  31 (4): 959-965

Chandarana, P; Iezzi, T; Girotti, M; Engel, C J; Girvan, D; Holliday, R; Cook, J
Psychosocial Adjustment in Couples Attending a Breast Clinic Canadian Psychiatric Association 1994: 56 – 57
Vezina, W C; McAlister, VC; Wall, WJ; Engel, C J; Grant, DR; Ghent CN; Hutton, LC; King, ME; Chey, WY  Normal Fasting Volume and Postprandial Emptying of the Denervated Donor Gallbladder in Liver Transplant Recipients Gastroenterology 1994; 107: 847-853

Engel, C J; Eilber, F R; Rosen, G; Selch, M T; Fu, Yao-Shi Pre-operative Chemotherapy for Soft Tissue Sarcomas of the Extremities:  The Experience at the University of California,  Los Angeles In:  Verwey J; Pinedo, H M; and Suit, H D; editors  Multidisciplinary Treatment of Soft Tissue Sarcomas, Kluwer Academic Publishers 1993: 135 – 141

Engel, C J; Meads, G E; Joseph, N G; et al Eccrine Spradenoma:  A Report of Malignant Transformation Canadian Journal of Surgery, 1991, 34(5): 477 – 480

RR Hammond, S Chakrabarti, BM Garcia, LF Pickard, JA Sinield, CJ Engel, JJ Gilbert, LM Koen, S Kodeeswaran, BW Zanke. The Ontario Tumour Bank: A Tumour Bank and Clinical Data Base Built for the 21st Century. Poster

R. George, A. B. Tuck, M.W. Lee, N. Hodgson, C. J. Engel, R. Holliday, D. Girvan, L. Scott, W. Al-Katif & a. F. Chambers “Predictors of Axillary Lymph Node Metastases In Patients Undergoing Sentinel Lymph Node Biopsy For Breast Cancer: Role of Osteopontin & Other Prognostic Factors” 54th Annual Meeting of the Canadian Association of Pathologists, Charlottetown, P.E.I., 2003
N. Hodgson,  A. G. Mattar, PL Zabel, C. J. Engel, R. L. Holliday, D. M. Grace:   London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada
“A New Radiocolloid For Sentinel Lymph Node Detection In Breast Cancer” 47th Annual Society Of Nuclear Medicine Meeting, St. Louis, June 2000

“Jumping Translocations in Leukemia and Lymphoma”   The American Journal of Human Genetics Annual Meeting  1999

Fan, Yao-Shan; Rizkalla, B F William; Engel, C J Interstitial Deletion of 8(q13q22) in Diffuse Large B-Cell Gastric Lymphoma   Cancer Genet Cytogenet 115:28-31 (1999)

Fan, Yao-Shan; Rizkalla, Brian F William; and Engel, C J Jumping Translocations in Leukemia and Lymphoma  The American Journal of Human Genetics, Volume 65, October 1999
Khalil, M; Crosby, J; Atkinson, P; Holliday, R L, Engel, C J; Doig, G S ; and O’Malley, F P  Stratification of Breast FNA Diagnoses into Clinically Useful Categories (not published)

G. Sheridan, P. J. Ainsworth, J. H. Jung, & C. J. Engel Familial Cancer Genetics Program, London Health Sciences Centre/London Regional Cencer Centre, London, Ontario Familial Breast and Ovarian Cancer: A Multidiciplinary Approach to Identifying High Risk Families in South Western Ontario.

Bennett, S; Engel, C J; O’Malley, F; Doig, G; and Chambers, A
Tumor Angiogenesis Predicts Metastasis in Invasive Colorectal Cancer;Modern Pathology 8:57A, 1995

Engel, C J; Eilber, F R; Rosen, G Pelvic Soft Tissue Sarcomas (abstract)  Proceedings of the American Society of Clinical Oncology, 1992

Engel, C J, Grant, D; Wall, W, et al Function of the Transplanted Gallbladder in Liver Recipients (abstract)  Clinical and Investigative Medicine  ll:C90;88

Vezina, W C; Chamberlain, G W; Engel, C J; et al Effects of hypertonic Carbohydrate Meals on Plasma CCK and Emptying of the Gallbladder and Stomach in Humans (abstract)

Annual Meeting of the American Gastroenterological Association (1987), Gastroenterology 1987: 92; 1683

Eiber, F R; Eckardt, J; Rosen, G; Engel, C J; Selch, M; Fu, Y S Extremity Preservation in Soft-Tissue Sarcomas:  Factors Related to Local Failure (abstract) Thirty-sixth Annual Clinical Conference and Twenty-fifth Annual Special Pathology Program:  Patterns and Mechanisms of Failure After Cancer Treatment.  April1 – 4, 1992 Houston, Texas  1992:5

Present Research Initiatives:
Characterization of the role of connexin43 and pannexins in human skin cancer.

A Phase III Randomized Study of Exemestane Plus Placebo Versus Exemestane Plus Celecoxib Versus Placebo In Postmenopausal Women at Increased Risk of Developing
Breast Cancer  NCIC TG Protocol # MAP.3  EXEAPO-0028-150 

A Phase III Randomized Study of Preoperative Radiation Plus Surgery Versus Surgery Alone for Patients with Retroperitoneal Sarcomas (RPS) Z09031           

A Prospective Study to Determine the Role of Positron Emission Tomography in the Assessment of Regional Nodal Spread of Disease in Breast Cancer Patients –
Steering Committee 2004

Ontario Cancer Genetics Network Ethics #E648  (Principal Investigator)

Ontario Familial Breast Cancer Registry Ethics #E5291 (Principal Investigator)

Ontario Familial Colon Cancer Registry Ethics #5752 (Principal Investigator)

Research Questionnaire for a Study of Breast and Ovarian Cancer in High Risk Families
(Principal Investigator

Validation of the Genetic Counselling Needs Assessment Questionnaire Ethics #E6484
(Principal Investigator)

A Survey of Quality of Life and Risk Perception in Individuals

Undergoing Familial-Genetic Assessment for Cancer Risk Ethics #5940 (Principal Investigator)

Qualitative Survey:  Familial Breast and Ovarian Cancer:  The Common Reasons That Brought Individuals Into Genetic Counselling for Breast and/or Ovarian Cancer
(Principal Investigator)

A Prospective Study of Prognosis in Heritable and Familial Breast Cancer
(Principal Investigator)

Prophylactic Bilateral Mastectomy in Ontario Ethics #6752 (Principal Investigator)

Research Funding:
• PSI (Physician Services Incorporated) Grant, $20,000, March 2008
• London Regional Cancer Program Small Grants Competition $25,000. Dec 2007
• Ontario Familial Breast Cancer Registry – Local PI, NIH total $90,000
• Ontario Familial Colon Cancer Registry – Local PI, total $15,000

Continuing Education:
• 2007              Defining Quality in Gastric Cancer Surgery, Cancer Care Ontario
• 2000-07         Canadian Surgical Forum
• 1996-07         Canadian Society of Surgical Oncologists Annual Meeting
• 1992–07        South Western Ontario Surgical Association Annual Meeting
• 2001–04        South Western Ontario Gastroenterology Association Annual  Meeting
• 2000, 2002, 2006, 2008,2009    Miami Beach Breast Cancer Conference
• 2001, 2004    NIH Human Participants Protection Education for Research Teams
• 2001              A Day With Dr Lazlo Tabar
• 2001              IMPACT Breast Cancer. A Regional Peer Education Program.
• 2001              Surgical Oncology Network Symposium
• 2000              Fourth National Community Cancer Conference
• 2000              Improving Communication Between Doctors and Breast Cancer Patients